
Whenever you gain life, target opponent loses that much life.
: Creatures you control gain lifelink until end of turn.
Vito turns every point of lifegain into direct drain, so you build a mono-black engine that gains life repeatedly and converts it into damage at every opponent. Early turns develop ramp and incremental lifegain, then you grind value until Vito's static ability quietly kills the table or you find a single big-payoff combo. His activated ability grants your whole board lifelink for an alpha strike that doubles as a life-loss bomb.
Add fast mana (Dark Ritual, Jet Medallion) and efficient tutors (Demonic Tutor, Vampiric Tutor, Diabolic Intent) to assemble the Exquisite Blood/Sanguine Bond combo more reliably. Layer in redundant drain effects (Cliffhaven Vampire, Marauding Blight-Priest, Vizkopa Guildmage) so removing Vito doesn't end the game, and run protection like Heroic Intervention proxies in black such as Malakir Rebirth and Imp's Mischief. Tighten the curve and cut win-more lifegain that doesn't trigger Vito enough times to matter.
The most-played cards for this commander, built from aggregated deck data (the Mythic Graph). Build public decks to seed it.
→ Infinite lifegain triggers, Infinite lifeloss, Infinite lifegain
→ Infinite lifegain triggers, Infinite lifeloss, Infinite lifegain
→ Target opponent loses the game, Infinite lifeloss for target opponent
→ Near-infinite lifegain, Near-infinite lifeloss for target opponent
→ Near-infinite lifegain, Near-infinite lifeloss for up to two target opponents
Combos via Commander Spellbook.
Same color identity (B), by popularity.